Chapter 658 Telomerase
Lin Hong looked through the book quickly.
When it comes to reading and learning knowledge, it has always been his strengths. At the age of a few years, he was able to learn by himself at a glance, let alone now.
In less than ten minutes, he had finished reading this large manual, and he also had the confidence to do some operations of the laboratory.
It is described in great detail. There are not only some operating specifications that need to be paid attention to when doing experiments, but also various operational essentials for doing experiments. It is very comprehensive, which is also the content that Lin Hong urgently needs now.
Seeing that he walked so fast and turned over, she couldn't help shaking her head slightly. She didn't understand what the boy was doing here. She didn't even know the most basic operation, and even came here to do experiments.
On the contrary, the big sister looks very professional, and all the experimental movements can be regarded as a standard model.
Maybe this boy is just her cousin or something? Did you come here just for fun?
The experiment in Hangqin's hand had been completed. He was about to go to Si Qian's side to see what experiment she was doing, but he saw that Lin Hong picked up the test tube and dropper again and began a new attempt.
This time, he put on special clothes, gloves and masks, and stared solemnly at the use of the dropper to transfer the blood sample in the test tube to a small petri dish...
When Hangqin was halfway there, he could no longer walk under his feet. He stared at a pair of big eyes, and his eyes were very surprised.
From Lin Hong, she actually saw the temperament of the tutor when doing experiments. When operating various instruments and utensils, it was clean and neat, and there was no superfluous action at all, just like an old experimenter who had been immersed in this field for more than ten years.
What's going on?
Hang Qin was puzzled. Did he do it on purpose just now?
At the thought that she had just run over and pointed at him, her face couldn't help but get a little hot.
This guy is so abominable. He must have done it on purpose just now, making a fool of himself!
No wonder Sister Si Qian laughed secretly there. I thought I was laughing at him, but I didn't expect him to laugh at me.
Under a burst of embarrassment, Hang Qin quickly said to Si Qian and left the laboratory. She really had no face to stay. She was really embarrassed just now.
Lin Hong didn't know that his abnormal learning ability made Hang Qin think of so many things, and all his mind was focused on the experiment.
He is now trying to isolate the cancer cells in the blood, and then find a way to destroy the telomerase that can preserve genetic information in cancer cells.
This process. First, the cancer cells are separated, then the cell wall of the cancer cells is decomposed by chemical means, and finally, the protein molecule called telomerase is found through his own special ability.
There is some difference between Si Qian's work and his.
What she has to do is to isolate the immune cells in the blood sample, then put them in a culture bottle, cultivate a large number of these immune cells externally in an artificial way, and then inject the cultured immune cells into the patient's body. See if you can kill cancer cells with the attack ability of immune cells.
For example, cancer cells and immune cells are like two opposing armies. They take the human body as the battlefield, and immune cells are the protectors. Once cancer cells are found to invade, they will immediately act and destroy them.
However, sometimes due to the surrounding environment, host eating habits and other diseases, it will affect the survival of immune cells, and once the immune cells are damaged, the cancer cells that have been staring at will take advantage of it. A large-scale invasion.
Once cancer cells occupy some advantages, this advantage will be like the butterfly effect, starting to gradually produce qualitative changes from quantitative change, and finally the initiative of the battlefield occupied by cancer cells to build a fortress and base camp (tumor tissue) on the battlefield. Declade victory completely.
At this time, under the pursuit of cancer cells, the number of immune cells is not only sparse, but also the combat effectiveness is correspondingly weakened, which can not affect the occupation at all.
What Si Qian has to do. It is to transfer a small strand of immune cell troops from the deteriorated "battlefield", put them in the new replication culture base (culture container), give sufficient nutrition and appropriate temperature, carry out a large number of artificial replication culture, restore the number and combat effectiveness to the original level, and then reinvest the new army. Go to the battlefield to fight against cancer cells.
If you can't do it once, you can do it twice or three times...
Anyway, the current cell culture technology can be easily carried out in the laboratory, and its speed is also very fast.
However, this method only stays in Si Qian's vision. Whether it can work or not must be confirmed by experiments, and will eventually be used in the specific treatment of patients.
Si Qian first isolated the cancer cells from Lin Changming's blood samples, and then injected these cancer cells into the mice's body to infect these cancer cells in the mice' cells and create "tumor patients".
Then, blood was extracted from the mice, immune cells were isolated, and the culture of immune cells began.
After a few days, when the tumor cells of the mice reach a certain level, the cultured immune cells will be injected into its body to check and record the specific situation of the experimental body at any time.
Lin Hong and Si Qian have taken root in this laboratory since then, especially Lin Hong, who seems to have returned to the state of sleeplessness when he was a child.
Of course, it's not that he didn't rest at all. He directly asked people to prepare a sleeping bag in the small room in the laboratory, and then rested according to Leonardo da Vinci's sleep method.
Leonardo da Vinci sleep method is a timed short-term sleep delay working method invented by the genius Leonardo da Vinci, which improves the efficiency of time utilization by adjusting the rigid regularity of sleep and not sleeping.
This method is very simple, that is, 15 minutes of sleep every four hours of work, so that the cumulative time spent on sleep is less than one and a half hours in total.
However, this sleep method has been questioned by many people, believing that it is unscientific to strictly stipulate the sleep time, because many people can't fall asleep in a very short time, and even lying in the brew of sleep for less than 15 minutes.
After testing, many people have proved that this method is very feasible, and it takes at least half an hour to two hours at a time.
Lin Hong has no obstacles to the practice of this method. Due to the existence of the superbrain system, he can accurately go to sleep on time. After fifteen minutes of rest, the whole person's spirit has indeed become energetic.
He even doubted whether Leonardo da Vinci had the same control over his body, including his brain, to a very fine point.
Today, Hangqin came to the laboratory before seven o'clock, but to her surprise, the light was still on in the laboratory at this time.
She opened the door and found that Lin Hong was still doing something in the laboratory.
"Don't he have to sleep?"
A huge question arises in Hangqin's mind. She found that no matter how early she arrived at the laboratory, she must be able to see that he was doing experiments, and no matter how late he left the laboratory, he left later than himself every time.
After Lin Hong saw her, he smiled and said, "Good morning."
"Good morning."
Hang Qin came to him and asked, "Have you had breakfast yet?"
While operating the experimental instrument, Lin Hong said, "Not yet. But when Si Qian comes back, she will bring it by the way.
At this time, Lin Hong took out a test tube with light blue ** from the incubator, put it in front of his eyes, and looked carefully.
"What is this?"
Lin Hong explained: "An enzyme inside the cell, according to the domestic translation, should be called telomerase."
As a doctoral student, Hang Qin naturally knows what telomerase is, which is an enzyme responsible for telomere extension.
Telomeres are a DNA fragment at the end of the chromosome.
For example, if the whole DNA structure is a long wool sleeve, then the telomeres are the part that has been delined at the cuffs.
After the cell divides, telomeres (incomplete delineated parts) will appear at the beginning and end of the chromosome, and this enzyme can repair the telomere of the chromosome and re-stitch the delined part to form a smooth whole.
In this way, the next time the cell is cloned and divided, there will be no loss of genetic information, which can increase the number of cell division and clones.
In ordinary normal cells, telomerase is very tightly regulated. Generally, after a certain number of divisions, the activity of this enzyme will gradually decrease. Without its protection, the life of the cell will gradually come to an end, because every division will be damaged.
Only in special cells such as hematopoietic cells, stem cells, and germ cells can the activity of telomerase be abnormally strong and can be detected.
Telomerase is related to the lifespan of cells, and the lifetime of cells is related to the lifespan of organs. Therefore, some scientists say that this enzyme is closely related to human lifespan. As long as the secret of telomerase is solved, the secret of human immortality will be solved.
However, telomerase is not so easy to separate, and the requirements for the process and environment are very strict. At the beginning, her tutor also did the separation experiment of telomerase. She remembered very well that she failed many times before she finally cultivated a small bottle.
Lin Hong was very surprised that she was able to cultivate such a pipe in such a short time.
Hang Qin thought of this and casually asked, "What cell's telomerase is this?"
Lin Hong's eyes showed a color of hope and said, "Cancer cells."
As long as I find a way to destroy this enzyme, I can cure my father's disease! Lin Hong said in his heart.
"Cancer cells?" Hang Qin was stunned when she heard the words. RQ